About Xofigo ®

Xofigo® is a new type of injected radiation used to treat prostate cancer that has spread to the bone. Although the radiation passes through your entire body, it only attacks cancer cells in your bone. Because of this, it has low side effects.

How It Works

Xofigo® is made of a radioactive substance called radium 223. It moves throughout your body and “hones in” on tumors in your bone to directly deliver radiation where it needs to go. The injection causes minimal damage to healthy tissue around the tumors and therefore side effects are minimal. 
Xofigo® is injected intravenously every four weeks for six months. The process only takes about one minute. 

What to Expect

Describe patient experience
Xofigo® is currently used only to treat metastatic castration-resistant prostate cancer (mCRPC) that has spread to your bone. It may be used alone or with other treatments, including hormone therapy.

Side Effects

Generally, Xofigo® has few side effects. The most common are nausea, diarrhea, vomiting, swelling of the arms and legs (edema) and low blood cell counts.
Many patients can often continue most of their normal daily activities with a reduced schedule, including working full time during their radiation therapy. 
Because Xofigo® injections contain a radioactive substance, there are some precautions you must take while receiving treatment to prevent exposing others. Good hygiene practices reduce others’ exposure to any bodily fluids, and you must use a condom during intercourse to prevent exposing your partner. There are no restrictions on causal contact with other people.
Talk with your radiation oncology team about any side effects you have while on Xofigo®. They can give you information about how to manage them and may prescribe medicines that can help provide relief.